Lataa...

Liver-Specific, but Not Retina-Specific, Hepcidin Knockout Causes Retinal Iron Accumulation and Degeneration

The liver secretes hepcidin (Hepc) into the bloodstream to reduce blood iron levels. Hepc accomplishes this by triggering degradation of the only known cellular iron exporter ferroportin in the gut, macrophages, and liver. We previously demonstrated that systemic Hepc knockout (HepcKO) mice, which h...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Am J Pathol
Päätekijät: Baumann, Bailey H., Shu, Wanting, Song, Ying, Sterling, Jacob, Kozmik, Zbynek, Lakhal-Littleton, Samira, Dunaief, Joshua L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Investigative Pathology 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6723216/
https://ncbi.nlm.nih.gov/pubmed/31287995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2019.05.022
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!