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Hepcidin and Ferroportin: The New Players in Iron Metabolism

Systemic iron homeostasis is regulated by the interaction of the peptide hormone, hepcidin and the iron exporter, ferroportin. Mutations in FPN1, the gene that encodes ferroportin, result in iron-overload disease that shows dominant inheritance and variation in phenotype. The inheritance of ferropor...

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Autores principales: De Domenico, Ivana, Ward, Diane McVey, Kaplan, Jerry
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3706197/
https://ncbi.nlm.nih.gov/pubmed/21901657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0031-1286058
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