Loading...

On the mechanism of iron sensing by IRP2: new players, new paradigms

Two iron regulatory proteins (IRP1 and IRP2) regulate translation and/or stability of mRNAs encoding proteins required for iron storage, acquisition and utilization. Rather than IRP2 directly sensing iron concentrations, iron has been shown to regulate the level of the SKP1-CUL1-FBXL5 E3 ubiquitin l...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Nat Chem Biol
Main Authors: Takahashi-Makise, Naoko, Ward, Diane McVey, Kaplan, Jerry
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4503334/
https://ncbi.nlm.nih.gov/pubmed/26190951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.261
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!