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Specific iron chelators determine the route of ferritin degradation

Deferoxamine (DFO) is a high-affinity Fe (III) chelator produced by Streptomyces pilosus. DFO is used clinically to remove iron from patients with iron overload disorders. Orally administered DFO cannot be absorbed, and therefore it must be injected. Here we show that DFO induces ferritin degradatio...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: De Domenico, Ivana, Ward, Diane McVey, Kaplan, Jerry
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society of Hematology 2009
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2777130/
https://ncbi.nlm.nih.gov/pubmed/19671920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-05-224188
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