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Specific iron chelators determine the route of ferritin degradation
Deferoxamine (DFO) is a high-affinity Fe (III) chelator produced by Streptomyces pilosus. DFO is used clinically to remove iron from patients with iron overload disorders. Orally administered DFO cannot be absorbed, and therefore it must be injected. Here we show that DFO induces ferritin degradatio...
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| Huvudupphovsmän: | , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
American Society of Hematology
2009
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2777130/ https://ncbi.nlm.nih.gov/pubmed/19671920 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-05-224188 |
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