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Induction of FPN1 transcription by MTF-1 reveals a role for ferroportin in transition metal efflux

Ferroportin (Fpn) is the only known iron exporter in vertebrate cells and plays a critical role in iron homeostasis regulating cytosolic iron levels and exporting iron to plasma. Ferroportin1 (FPN1) expression can be transcriptionally regulated by iron as well as other transition metals. Fpn can als...

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Detalhes bibliográficos
Main Authors: Troadec, Marie-Berengere, Ward, Diane McVey, Lo, Eric, Kaplan, Jerry, De Domenico, Ivana
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996121/
https://ncbi.nlm.nih.gov/pubmed/20688958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-04-278614
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