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Induction of FPN1 transcription by MTF-1 reveals a role for ferroportin in transition metal efflux
Ferroportin (Fpn) is the only known iron exporter in vertebrate cells and plays a critical role in iron homeostasis regulating cytosolic iron levels and exporting iron to plasma. Ferroportin1 (FPN1) expression can be transcriptionally regulated by iron as well as other transition metals. Fpn can als...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society of Hematology
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2996121/ https://ncbi.nlm.nih.gov/pubmed/20688958 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-04-278614 |
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