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The ABBA motif binds APC/C activators and is shared by APC/C substrates and regulators

The APC/C is the ubiquitin ligase that regulates mitosis by targeting specific proteins for degradation at specific times under the control of the Spindle Assembly Checkpoint (SAC). How the APC/C recognises its different substrates is a key problem in the control of cell division. Here, we have iden...

詳細記述

保存先:
書誌詳細
出版年:Dev Cell
主要な著者: Di Fiore, Barbara, Davey, Norman E., Hagting, Anja, Izawa, Daisuke, Mansfeld, Jörg, Gibson, Toby J., Pines, Jonathon
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4713905/
https://ncbi.nlm.nih.gov/pubmed/25669885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2015.01.003
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