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UBE2S elongates ubiquitin chains on APC/C substrates to promote mitotic exit
The anaphase-promoting complex (APC/C) ubiquitin ligase is the target of the spindle-assembly checkpoint (SAC), ubiquitylating protein substrates whose degradation regulates progress through mitosis1-3. The identity of the ubiquitin-conjugating (E2) enzymes that work with the APC/C is unclear. In an...
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| Auteurs principaux: | , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2875106/ https://ncbi.nlm.nih.gov/pubmed/19820702 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb1983 |
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