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Efficient APC/C substrate degradation in cells undergoing mitotic exit depends on K11 ubiquitin linkages
The ubiquitin proteasome system (UPS) directs programmed destruction of key cellular regulators via posttranslational modification of its targets with polyubiquitin chains. These commonly contain Lys-48 (K48)–directed ubiquitin linkages, but chains containing atypical Lys-11 (K11) linkages also targ...
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| Udgivet i: | Mol Biol Cell |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The American Society for Cell Biology
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4666129/ https://ncbi.nlm.nih.gov/pubmed/26446837 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E15-02-0102 |
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