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Deubiquitinase–based analysis of ubiquitin chain architecture using Ubiquitin Chain Restriction (UbiCRest)

Protein ubiquitination is a versatile protein modification that regulates virtually all cellular processes. This versatility originates from polyubiquitin chains, which can be linked in eight distinct ways. The combinatorial complexity of eight linkage types in homotypic (one chain type per polymer)...

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Bibliographic Details
Published in:Nat Protoc
Main Authors: Hospenthal, Manuela K., Mevissen, Tycho E.T., Komander, David
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5011418/
https://ncbi.nlm.nih.gov/pubmed/25633630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2015.018
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