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The Mitotic Checkpoint Complex Requires an Evolutionary Conserved Cassette to Bind and Inhibit Active APC/C

The Spindle Assembly Checkpoint (SAC) ensures genomic stability by preventing sister chromatid separation until all chromosomes are attached to the spindle. It catalyzes the production of the Mitotic Checkpoint Complex (MCC), which inhibits Cdc20 to inactivate the Anaphase Promoting Complex/Cyclosom...

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Bibliografiset tiedot
Julkaisussa:Mol Cell
Päätekijät: Di Fiore, Barbara, Wurzenberger, Claudia, Davey, Norman E., Pines, Jonathon
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Cell Press 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5179498/
https://ncbi.nlm.nih.gov/pubmed/27939943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.11.006
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