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Evaluation of AKT phosphorylation and PTEN loss and their correlation with the resistance of rituximab in DLBCL
Background: Diffuse large B-cell lymphoma (DLBCL) is the most common subtype of lymphoma with quite high mortality. PTEN/PI3K/AKT signal pathway is constitutively activated and plays an oncogenic role in most tumors including non-Hodgkin’s lymphoma (NHL). Since rituximab used in chemotherapy has bee...
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| Veröffentlicht in: | Int J Clin Exp Pathol |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
e-Century Publishing Corporation
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4713603/ https://ncbi.nlm.nih.gov/pubmed/26823817 |
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