Evaluation of AKT phosphorylation and PTEN loss and their correlation with the resistance of rituximab in DLBCL

Background: Diffuse large B-cell lymphoma (DLBCL) is the most common subtype of lymphoma with quite high mortality. PTEN/PI3K/AKT signal pathway is constitutively activated and plays an oncogenic role in most tumors including non-Hodgkin’s lymphoma (NHL). Since rituximab used in chemotherapy has bee...

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Detaylı Bibliyografya
Yayımlandı:Int J Clin Exp Pathol
Asıl Yazarlar: Ma, Yihui, Zhang, Pengyu, Gao, Yi, Fan, Huijie, Zhang, Mingzhi, Wu, Jingjing
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: e-Century Publishing Corporation 2015
Konular:
Original Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4713603/
https://ncbi.nlm.nih.gov/pubmed/26823817
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