EVIDENCE OF THE IMPORTANCE OF NOX4 IN PRODUCTION OF HYPERTENSION IN DAHL SALT-SENSITIVE RATS

This study reports the consequences of knocking out NADPH oxidase 4 (Nox4) upon the development of hypertension and kidney injury in the Dahl salt-sensitive (SS) rat. Zinc finger nuclease injection of single cell SS embryos was used to create an 8 base-pair frame-shift deletion of Nox4 resulting in...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Hypertension
मुख्य लेखकों: Cowley, Allen W., Yang, Chun, Zheleznova, Nadezhda N., Staruschenko, Alexander, Kurth, Theresa, Rein, Lisa, Kumar, Vikash, Sadovnikov, Katherine, Dayton, Alex, Hoffman, Matthew, Ryan, Robert P., Skelton, Meredith M., Salehpour, Fahimeh, Ranji, Mahsa, Geurts, Aron
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2015
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4713301/
https://ncbi.nlm.nih.gov/pubmed/26644237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.115.06280
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