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Therapeutic Suppression of mTOR Signaling Prevents and Reverses Salt-Induced Hypertension and Kidney Injury in Dahl Salt-Sensitive Rats
Mammalian target of rapamycin (mTOR) signaling has emerged as a key regulator in a wide range of cellular processes ranging from cell proliferation, immune responses, and electrolyte homeostasis. mTOR consists of two distinct protein complexes mTORC1 and mTORC2, each with distinct downstream signali...
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| Publicado no: | Hypertension |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6374175/ https://ncbi.nlm.nih.gov/pubmed/30595123 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.118.12378 |
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