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Inhibition of mTORC1 attenuates salt-induced hypertension and kidney injury in Dahl salt-sensitive rats

The goal of the present study was to explore the protective effects of mTORC1 inhibition by rapamycin on salt-induced hypertension and kidney injury in Dahl salt-sensitive (SS) rats. We have previously demonstrated that H(2)O(2) is elevated in the kidneys of SS rats. The present study showed a signi...

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Detalhes bibliográficos
Publicado no:Hypertension
Main Authors: Kumar, Vikash, Wollner, Clayton, Kurth, Theresa, Bukowy, John, Cowley, Allen W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5599353/
https://ncbi.nlm.nih.gov/pubmed/28827472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.117.09456
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