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Chicken scFvs with an Artificial Cysteine for Site-Directed Conjugation

For the site-directed conjugation of chemicals and radioisotopes to the chicken-derived single-chain variable fragment (scFv), we investigated amino acid residues replaceable with cysteine. By replacing each amino acid of the 157 chicken variable region framework residues (FR, 82 residues on V(H) an...

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Bibliografiset tiedot
Julkaisussa:PLoS One
Päätekijät: Yoon, Aerin, Shin, Jung Won, Kim, Soohyun, Kim, Hyori, Chung, Junho
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4713166/
https://ncbi.nlm.nih.gov/pubmed/26764487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0146907
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