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Chicken scFvs with an Artificial Cysteine for Site-Directed Conjugation

For the site-directed conjugation of chemicals and radioisotopes to the chicken-derived single-chain variable fragment (scFv), we investigated amino acid residues replaceable with cysteine. By replacing each amino acid of the 157 chicken variable region framework residues (FR, 82 residues on V(H) an...

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Pubblicato in:PLoS One
Autori principali: Yoon, Aerin, Shin, Jung Won, Kim, Soohyun, Kim, Hyori, Chung, Junho
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4713166/
https://ncbi.nlm.nih.gov/pubmed/26764487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0146907
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