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Chicken scFvs with an Artificial Cysteine for Site-Directed Conjugation

For the site-directed conjugation of chemicals and radioisotopes to the chicken-derived single-chain variable fragment (scFv), we investigated amino acid residues replaceable with cysteine. By replacing each amino acid of the 157 chicken variable region framework residues (FR, 82 residues on V(H) an...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Yoon, Aerin, Shin, Jung Won, Kim, Soohyun, Kim, Hyori, Chung, Junho
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4713166/
https://ncbi.nlm.nih.gov/pubmed/26764487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0146907
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