Differential regulation of inflammation and apoptosis in Fas-resistant hepatocyte-specific Bid-deficient mice

BACKGOUND & AIMS: Activation of Fas death receptor results in apoptosis in multiple organs, particularly liver, in a process dependent on Bid cleavage. Mice injected with an anti-Fas antibody die within hours of acute liver failure associated with massive apoptosis and hemorrhage. Our aim was to...

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Udgivet i:J Hepatol
Main Authors: Lazic, Milos, Eguchi, Akiko, Berk, Michael P., Povero, Davide, Papouchado, Bettina, Mulya, Anny, Johnson, Casey D., Feldstein, Ariel E.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4712949/
https://ncbi.nlm.nih.gov/pubmed/24681344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2014.03.028
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