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Hepatocyte-specific Bid depletion reduces tumor development by suppressing inflammation-related compensatory proliferation

Liver cancer is a major health-care concern and its oncogenic mechanisms are still largely unclear. Persistent hepatocyte cell death is a common feature among various chronic liver diseases, the blocking of which presents as logical treatment. Therefore, we aimed at investigating tumor development i...

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Wree, A, Johnson, C D, Font-Burgada, J, Eguchi, A, Povero, D, Karin, M, Feldstein, A E
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4816107/
https://ncbi.nlm.nih.gov/pubmed/25909884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2015.46
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