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Caspase-3 suppresses diethylnitrosamine-induced hepatocyte death, compensatory proliferation and hepatocarcinogenesis through inhibiting p38 activation

It is critical to understand the molecular mechanisms of hepatocarcinogenesis in order to prevent or treat hepatocellular carcinoma (HCC). The development of HCC is commonly associated with hepatocyte death and compensatory proliferation. However, the role of Caspase-3, a key apoptotic executor, in...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Shang, Na, Bank, Thomas, Ding, Xianzhong, Breslin, Peter, Li, Jun, Shi, Baomin, Qiu, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5948202/
https://ncbi.nlm.nih.gov/pubmed/29752472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0617-7
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