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The Matricellular Protein CCN1 Suppresses Hepatocarcinogenesis by Inhibiting Compensatory Proliferation

Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related deaths worldwide, and is on the rise in the United States. Previous studies showed that the matricellular protein CCN1 (CYR61) is induced during hepatic injuries and functions to restrict and resolve liver fibrosis. Here we...

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Vydáno v:Oncogene
Hlavní autoři: Chen, Chih-Chiun, Kim, Ki-Hyun, Lau, Lester F.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4666840/
https://ncbi.nlm.nih.gov/pubmed/26028023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2015.190
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