Functions and Mechanisms of Action of CCN Matricellular Proteins

Por Chen, Chih-Chiun, Lau, Lester F.
Publicado em 2008

Deadly liaisons: fatal attraction between CCN matricellular proteins and the tumor necrosis factor family of cytokines

Por Chen, Chih-Chiun, Lau, Lester F.
Publicado em 2009

Fas-Mediated Apoptosis Is Regulated by the Extracellular Matrix Protein CCN1 (CYR61) In Vitro and In Vivo

Por Juric, Vladislava, Chen, Chih-Chiun, Lau, Lester F.
Publicado em 2009

The Matricellular Protein CCN1 Activates a Pro-inflammatory Genetic Program in Murine Macrophages

Por Bai, Tao, Chen, Chih-Chiun, Lau, Lester F.
Publicado em 2010

TNFα-Induced Apoptosis Enabled by CCN1/CYR61: Pathways of Reactive Oxygen Species Generation and Cytochrome c Release

Por Juric, Vladislava, Chen, Chih-Chiun, Lau, Lester F.
Publicado em 2012

The Extracellular Matrix Protein CCN1 Dictates TNFα and FasL Cytotoxicity In Vivo

Por Chen, Chih-Chiun, Juric, Vladislava, Lau, Lester F.
Publicado em 2011

Fisp12/Mouse Connective Tissue Growth Factor Mediates Endothelial Cell Adhesion and Migration through Integrin α(v)β(3), Promotes Endothelial Cell Survival, and Induces Angiogenesi...

Por Babic, Alexander M., Chen, Chih-Chiun, Lau, Lester F.
Publicado em 1999

The Matricellular Protein CCN1 Suppresses Hepatocarcinogenesis by Inhibiting Compensatory Proliferation

Por Chen, Chih-Chiun, Kim, Ki-Hyun, Lau, Lester F.
Publicado no Oncogene (2015)

The matrix protein CCN1 (CYR61) induces apoptosis in fibroblasts

Por Todorovicç, Viktor, Chen, Chih-Chiun, Hay, Nissim, Lau, Lester F.
Publicado em 2005

CCN1 induces hepatic ductular reaction through integrin α(v)β(5)–mediated activation of NF-κB

Por Kim, Ki-Hyun, Chen, Chih-Chiun, Alpini, Gianfranco, Lau, Lester F.
Publicado no J Clin Invest (2015)

Matricellular Protein CCN1 Promotes Regression of Liver Fibrosis through Induction of Cellular Senescence in Hepatic Myofibroblasts

Por Kim, Ki-Hyun, Chen, Chih-Chiun, Monzon, Ricardo I., Lau, Lester F.
Publicado em 2013

Cytotoxicity of TNFα is regulated by integrin-mediated matrix signaling

Por Chen, Chih-Chiun, Young, Jennifer L, Monzon, Ricardo I, Chen, Ningyu, Todorović, Viktor, Lau, Lester F
Publicado em 2007

The Matrix Protein CCN1 is Critical for Prostate Carcinoma Cell Proliferation and TRAIL-Induced Apoptosis

Por Franzen, Carrie A., Chen, Chih-Chiun, Todorović, Viktor, Juric, Vladislava, Monzon, Ricardo I., Lau, Lester F.
Publicado em 2009

CYR61 (CCN1) Is Essential for Placental Development and Vascular Integrity

Por Mo, Fan-E, Muntean, Andrew G., Chen, Chih-Chiun, Stolz, Donna B., Watkins, Simon C., Lau, Lester F.
Publicado em 2002