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The Matricellular Protein CCN1 Activates a Pro-inflammatory Genetic Program in Murine Macrophages

CCN1 (CYR61) is a matricellular protein that is highly expressed at sites of inflammation and wound repair. In these contexts, CCN1 can modify the activities of specific cytokines, enabling TNFα to be cytotoxic without blocking NFκB activity and enhancing the apoptotic activity of FasL and TRAIL. He...

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Bibliografische gegevens
Hoofdauteurs: Bai, Tao, Chen, Chih-Chiun, Lau, Lester F.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2832719/
https://ncbi.nlm.nih.gov/pubmed/20164416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0902792
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