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The Matricellular Protein CCN1 Activates a Pro-inflammatory Genetic Program in Murine Macrophages
CCN1 (CYR61) is a matricellular protein that is highly expressed at sites of inflammation and wound repair. In these contexts, CCN1 can modify the activities of specific cytokines, enabling TNFα to be cytotoxic without blocking NFκB activity and enhancing the apoptotic activity of FasL and TRAIL. He...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2832719/ https://ncbi.nlm.nih.gov/pubmed/20164416 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0902792 |
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