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Cytotoxicity of TNFα is regulated by integrin-mediated matrix signaling
Cytokines of the tumor necrosis factor (TNF) family regulate inflammation and immunity, and a subset of this family can also induce cell death in a context-dependent manner. Although TNFα is cytotoxic to certain tumor cell lines, it induces apoptosis in normal cells only when NFκB signaling is block...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1817641/ https://ncbi.nlm.nih.gov/pubmed/17318182 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601596 |
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