Transcription coactivator PBP/MED1-deficient hepatocytes are not susceptible to diethylnitrosamine-induced hepatocarcinogenesis in the mouse

Nuclear receptor coactivator [peroxisome proliferator-activated receptor-binding protein (PBP)/mediator subunit 1 (MED1)] is a critical component of the mediator transcription complex. Disruption of this gene in the mouse results in embryonic lethality. Using the PBP/MED1 liver conditional null (PBP...

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Detalhes bibliográficos
Main Authors: Matsumoto, Kojiro, Huang, Jiansheng, Viswakarma, Navin, Bai, Liang, Jia, Yuzhi, Zhu, Yiwei Tony, Yang, Gongshe, Borensztajn, Jayme, Rao, M.Sambasiva, Zhu, Yi-Jun, Reddy, Janardan K.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Carcinogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812575/
https://ncbi.nlm.nih.gov/pubmed/20007298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgp306
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