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Transcription Coactivator Mediator Subunit Med1 is Required for the Development of Fatty Liver in the Mouse

Peroxisome proliferator-activated receptor-γ (PPARγ), a nuclear receptor, when overexpressed in liver stimulates the induction of adipocyte-specific and lipogenesis-related genes and causes hepatic steatosis. We report here that MED1 (also known as PBP or TRAP220) a key subunit of the Mediator compl...

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Détails bibliographiques
Auteurs principaux: Bai, Liang, Jia, Yuzhi, Viswakarma, Navin, Huang, Jiansheng, Vluggens, Aurore, Wolins, Nathan E., Jafari, Nadereh, Rao, M. Sambasiva, Borensztajn, Jayme, Yang, Gongshe, Reddy, Janardan K.
Format: Artigo
Langue:Inglês
Publié: 2011
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3076129/
https://ncbi.nlm.nih.gov/pubmed/21480322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.24155
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