The histone H2A deubiquitinase Usp16 regulates hematopoiesis and hematopoietic stem cell function

Epigenetic mechanisms play important regulatory roles in hematopoiesis and hematopoietic stem cell (HSC) function. Subunits of polycomb repressive complex 1 (PRC1), the major histone H2A ubiquitin ligase, are critical for both normal and pathological hematopoiesis; however, it is unclear which of th...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Gu, Yue, Jones, Amanda E., Yang, Wei, Liu, Shanrun, Dai, Qian, Liu, Yudong, Swindle, C. Scott, Zhou, Dewang, Zhang, Zhuo, Ryan, Thomas M., Townes, Tim M., Klug, Christopher A., Chen, Dongquan, Wang, Hengbin
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4711844/
https://ncbi.nlm.nih.gov/pubmed/26699484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1517041113
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