USP49 deubiquitinates histone H2B and regulates cotranscriptional pre-mRNA splicing

Post-translational histone modifications play important roles in regulating chromatin structure and function. Histone H2B ubiquitination and deubiquitination have been implicated in transcriptional regulation, but the function of H2B deubiquitination is not well defined, particularly in higher eukar...

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Hlavní autoři: Zhang, Zhuo, Jones, Amanda, Joo, Heui-Yun, Zhou, Dewang, Cao, Ying, Chen, Shaoxia, Erdjument-Bromage, Hediye, Renfrow, Matthew, He, Hang, Tempst, Paul, Townes, Tim M., Giles, Keith E., Ma, Ligeng, Wang, Hengbin
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2013
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Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3731547/
https://ncbi.nlm.nih.gov/pubmed/23824326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.211037.112
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