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Role of hPHF1 in H3K27 Methylation and Hox Gene Silencing

Polycomb group (PcG) proteins are required for maintaining the silent state of the homeotic genes and other important developmental regulators. The silencing function of the PcG proteins has been linked to their intrinsic histone modifying enzymatic activities. The EED-EZH2 complex, containing the c...

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Autori principali: Cao, Ru, Wang, Hengbin, He, Jin, Erdjument-Bromage, Hediye, Tempst, Paul, Zhang, Yi
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2258785/
https://ncbi.nlm.nih.gov/pubmed/18086877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01589-07
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