The histone H2A deubiquitinase Usp16 regulates hematopoiesis and hematopoietic stem cell function

Epigenetic mechanisms play important regulatory roles in hematopoiesis and hematopoietic stem cell (HSC) function. Subunits of polycomb repressive complex 1 (PRC1), the major histone H2A ubiquitin ligase, are critical for both normal and pathological hematopoiesis; however, it is unclear which of th...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Gu, Yue, Jones, Amanda E., Yang, Wei, Liu, Shanrun, Dai, Qian, Liu, Yudong, Swindle, C. Scott, Zhou, Dewang, Zhang, Zhuo, Ryan, Thomas M., Townes, Tim M., Klug, Christopher A., Chen, Dongquan, Wang, Hengbin
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2016
Soggetti:
PNAS Plus
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4711844/
https://ncbi.nlm.nih.gov/pubmed/26699484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1517041113
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