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Receptor editing and genetic variability in human autoreactive B cells
The mechanisms by which B cells undergo tolerance, such as receptor editing, clonal deletion, and anergy, have been established in mice. However, corroborating these mechanisms in humans remains challenging. To study how autoreactive human B cells undergo tolerance, we developed a novel humanized mo...
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| Publicado no: | J Exp Med |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4710202/ https://ncbi.nlm.nih.gov/pubmed/26694971 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20151039 |
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