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S1P3 confers differential S1P migration by autoreactive and non-autoreactive immature B cells and is required for normal B cell development

During B cell development, immature B cell fate is determined by whether the B cell antigen receptor is engaged in the bone marrow. Immature B cells that are non-autoreactive continue maturation and emigrate from the marrow whereas autoreactive immature B cells remain and are tolerized. However, the...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Donovan, Erin E., Pelanda, Roberta, Torres, Raul M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2924669/
https://ncbi.nlm.nih.gov/pubmed/20039302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200939858
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