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BAFF-R signaling aids the differentiation of immature B cells into transitional B cells following tonic BCR signaling
BAFF is an important pro-survival cytokine for mature B cells. However, previous studies have shown that the BAFF receptor, BAFF-R, is already expressed at the immature B cell stage, and that the pro-survival protein Bcl-2 does not completely complement the B cell defects resulting from the absence...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2950883/ https://ncbi.nlm.nih.gov/pubmed/20861359 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1001708 |
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