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BAFF-R signaling aids the differentiation of immature B cells into transitional B cells following tonic BCR signaling

BAFF is an important pro-survival cytokine for mature B cells. However, previous studies have shown that the BAFF receptor, BAFF-R, is already expressed at the immature B cell stage, and that the pro-survival protein Bcl-2 does not completely complement the B cell defects resulting from the absence...

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Hlavní autoři: Rowland, Sarah L., Leahy, Katelyn F., Halverson, Regina, Torres, Raul M., Pelanda, Roberta
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950883/
https://ncbi.nlm.nih.gov/pubmed/20861359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1001708
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