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Molecular mechanism of peptide editing in the tapasin–MHC I complex
Immune recognition of infected or malignantly transformed cells relies on antigenic peptides exposed at the cell surface by major histocompatibility complex class I (MHC I) molecules. Selection and loading of peptides onto MHC I is orchestrated by the peptide-loading complex (PLC), a multiprotein as...
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Publicado no: | Sci Rep |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4709564/ https://ncbi.nlm.nih.gov/pubmed/26754481 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19085 |
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