ERAAP and Tapasin independently edit the amino and carboxyl termini of MHC class I peptides

Effective CD8+ T cell responses depend upon presentation of a stable peptide repertoire by MHC I molecules on the cell surface. The overall quality of pMHC I is determined by poorly understood mechanisms that generate and load peptides with appropriate consensus motifs onto MHC I. Here we show that...

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Bibliografiske detaljer
Main Authors: Kanaseki, Takayuki, Lind, Kristin Camfield, Escobar, Hernando, Nagarajan, Niranjana, Reyes-Vargas, Eduardo, Rudd, Brant, Rockwood, Alan L., Van Kaer, Luc, Sato, Noriyuki, Delgado, Julio C., Shastri, Nilabh
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3735839/
https://ncbi.nlm.nih.gov/pubmed/23863903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301043
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