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Monitoring peptide processing for MHC class I molecules in the endoplasmic reticulum

Classical MHC class I molecules open a window into the cell by presenting intracellular peptides (pMHC I) on the surface. The peptides are used for immune surveillance by circulating CD8+ T and NK cells to detect and eliminate infected or tumor cells. Not surprisingly, viruses and tumor cells have e...

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Bibliografiske detaljer
Main Authors: Shastri, Nilabh, Nagarajan, Niranjana, Lind, Kristin C., Kanaseki, Takayuki
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3932006/
https://ncbi.nlm.nih.gov/pubmed/24556408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2013.11.006
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