Endoplasmic Reticulum Aminopeptidase Associated with Antigen Processing Defines the Composition and Structure of MHC Class I Peptide Repertoire in Normal and Virus-Infected Cells

The MHC class I (MHC-I) molecules ferry a cargo of peptides to the cell surface as potential ligands for CD8(+) cytotoxic T cells. For nearly 20 years, the cargo has been described as a collection of short 8-9 mer peptides, whose length and sequences were believed to be primarily determined by the p...

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Bibliografiske detaljer
Main Authors: Blanchard, Nicolas, Kanaseki, Takayuki, Escobar, Hernando, Delebecque, Frédéric, Nagarajan, Niranjana A., Reyes-Vargas, Eduardo, Crockett, David K., Raulet, David H., Delgado, Julio C., Shastri, Nilabh
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3087292/
https://ncbi.nlm.nih.gov/pubmed/20173027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0903712
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