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Coping with loss of perfection in the MHC class I peptide repertoire
The MHC class I molecules present thousands of peptides (pMHC I) on the cell surface for immune surveillance by CD8 T cells. The pMHC I repertoire normally contains peptides of perfect length and sequences suitable for binding each MHC I. The peptides are made by first fragmenting cytoplasmic protei...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2705891/ https://ncbi.nlm.nih.gov/pubmed/18243675 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2007.12.004 |
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