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Monitoring peptide processing for MHC class I molecules in the endoplasmic reticulum
Classical MHC class I molecules open a window into the cell by presenting intracellular peptides (pMHC I) on the surface. The peptides are used for immune surveillance by circulating CD8+ T and NK cells to detect and eliminate infected or tumor cells. Not surprisingly, viruses and tumor cells have e...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2013
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3932006/ https://ncbi.nlm.nih.gov/pubmed/24556408 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2013.11.006 |
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