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ERAAP and Tapasin independently edit the amino and carboxyl termini of MHC class I peptides
Effective CD8+ T cell responses depend upon presentation of a stable peptide repertoire by MHC I molecules on the cell surface. The overall quality of pMHC I is determined by poorly understood mechanisms that generate and load peptides with appropriate consensus motifs onto MHC I. Here we show that...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3735839/ https://ncbi.nlm.nih.gov/pubmed/23863903 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301043 |
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