Interaction of TAPBPR, a tapasin homolog, with MHC-I molecules promotes peptide editing

Peptide loading of major histocompatibility complex class I (MHC-I) molecules is central to antigen presentation, self-tolerance, and CD8(+) T-cell activation. TAP binding protein, related (TAPBPR), a widely expressed tapasin homolog, is not part of the classical MHC-I peptide-loading complex (PLC)....

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Morozov, Giora I., Zhao, Huaying, Mage, Michael G., Boyd, Lisa F., Jiang, Jiansheng, Dolan, Michael A., Venna, Ramesh, Norcross, Michael A., McMurtrey, Curtis P., Hildebrand, William, Schuck, Peter, Natarajan, Kannan, Margulies, David H.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4776512/
https://ncbi.nlm.nih.gov/pubmed/26869717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1519894113
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