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Structural basis of mouse cytomegalovirus m152/gp40 interaction with RAE1γ reveals a paradigm for MHC/MHC interaction in immune evasion

Natural killer (NK) cells are activated by engagement of the NKG2D receptor with ligands on target cells stressed by infection or tumorigenesis. Several human and rodent cytomegalovirus (CMV) immunoevasins down-regulate surface expression of NKG2D ligands. The mouse CMV MHC class I (MHC-I)–like m152...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Wang, Rui, Natarajan, Kannan, Revilleza, Maria Jamela R., Boyd, Lisa F., Zhi, Li, Zhao, Huaying, Robinson, Howard, Margulies, David H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3529088/
https://ncbi.nlm.nih.gov/pubmed/23169621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1214088109
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