Tapasin-related protein TAPBPR is an additional component of the MHC class I presentation pathway

Tapasin is an integral component of the peptide-loading complex (PLC) important for efficient peptide loading onto MHC class I molecules. We investigated the function of the tapasin-related protein, TAPBPR. Like tapasin, TAPBPR is widely expressed, IFN-γ–inducible, and binds to MHC class I coupled w...

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Main Authors: Boyle, Louise H., Hermann, Clemens, Boname, Jessica M., Porter, Keith M., Patel, Peysh A., Burr, Marian L., Duncan, Lidia M., Harbour, Michael E., Rhodes, David A., Skjødt, Karsten, Lehner, Paul J., Trowsdale, John
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2013
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3587277/
https://ncbi.nlm.nih.gov/pubmed/23401559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1222342110
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