Tapasin-related protein TAPBPR is an additional component of the MHC class I presentation pathway

Tapasin is an integral component of the peptide-loading complex (PLC) important for efficient peptide loading onto MHC class I molecules. We investigated the function of the tapasin-related protein, TAPBPR. Like tapasin, TAPBPR is widely expressed, IFN-γ–inducible, and binds to MHC class I coupled w...

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Bibliographic Details
Main Authors: Boyle, Louise H., Hermann, Clemens, Boname, Jessica M., Porter, Keith M., Patel, Peysh A., Burr, Marian L., Duncan, Lidia M., Harbour, Michael E., Rhodes, David A., Skjødt, Karsten, Lehner, Paul J., Trowsdale, John
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2013
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3587277/
https://ncbi.nlm.nih.gov/pubmed/23401559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1222342110
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