Tapasin-related protein TAPBPR is an additional component of the MHC class I presentation pathway

Tapasin is an integral component of the peptide-loading complex (PLC) important for efficient peptide loading onto MHC class I molecules. We investigated the function of the tapasin-related protein, TAPBPR. Like tapasin, TAPBPR is widely expressed, IFN-γ–inducible, and binds to MHC class I coupled w...

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Detalhes bibliográficos
Main Authors: Boyle, Louise H., Hermann, Clemens, Boname, Jessica M., Porter, Keith M., Patel, Peysh A., Burr, Marian L., Duncan, Lidia M., Harbour, Michael E., Rhodes, David A., Skjødt, Karsten, Lehner, Paul J., Trowsdale, John
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3587277/
https://ncbi.nlm.nih.gov/pubmed/23401559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1222342110
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