Tapasin-related protein TAPBPR is an additional component of the MHC class I presentation pathway

Tapasin is an integral component of the peptide-loading complex (PLC) important for efficient peptide loading onto MHC class I molecules. We investigated the function of the tapasin-related protein, TAPBPR. Like tapasin, TAPBPR is widely expressed, IFN-γ–inducible, and binds to MHC class I coupled w...

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Bibliografiska uppgifter
Huvudupphovsmän: Boyle, Louise H., Hermann, Clemens, Boname, Jessica M., Porter, Keith M., Patel, Peysh A., Burr, Marian L., Duncan, Lidia M., Harbour, Michael E., Rhodes, David A., Skjødt, Karsten, Lehner, Paul J., Trowsdale, John
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2013
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3587277/
https://ncbi.nlm.nih.gov/pubmed/23401559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1222342110
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