TAPBPR alters MHC class I peptide presentation by functioning as a peptide exchange catalyst

Our understanding of the antigen presentation pathway has recently been enhanced with the identification that the tapasin-related protein TAPBPR is a second major histocompatibility complex (MHC) class I-specific chaperone. We sought to determine whether, like tapasin, TAPBPR can also influence MHC...

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Publicado en:eLife
Autores principales: Hermann, Clemens, van Hateren, Andy, Trautwein, Nico, Neerincx, Andreas, Duriez, Patrick J, Stevanović, Stefan, Trowsdale, John, Deane, Janet E, Elliott, Tim, Boyle, Louise H
Formato: Artigo
Lenguaje:Inglês
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Cell Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4718805/
https://ncbi.nlm.nih.gov/pubmed/26439010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.09617
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