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The Pregnane X Receptor in Tuberculosis Therapeutics
INTRODUCTION: Among the infectious diseases, tuberculosis (TB) remains the second cause of death after HIV. TB treatment requires the combination of multiple drugs including the rifamycin class. However, rifamycins are activators of human pregnane X receptor (PXR), a transcription factor that regula...
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| Publicado no: | Expert Opin Drug Metab Toxicol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4708888/ https://ncbi.nlm.nih.gov/pubmed/26592418 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/17425255.2016.1121381 |
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